To Clement, though, my age was great news. “Yep, you are going to live forever,” he said. “I think anybody under 50 who does not have a genetic liability will make it to longevity escape velocity.”
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With funds from wealthy elderly men he knows, he is independently exploring drugs known to extend the healthy life span of rodents. Using a calculator, he extrapolates what a suitable human dose might be, and then finds people who will take them.
If he thinks the results look safe and have a hint of promise, he will recommend the treatments to his parents, who are in their 90s, and to his financial supporters.
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One potential aging treatment he is giving some 30 volunteers is a drug combination identified in 2015 at the Mayo Clinic by researcher James Kirkland as a way to selectively kill malfunctioning “senescent” cells in mice. Kirkland this year published his own pilot study exploring his treatment in 26 volunteers with pulmonary disease.
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Kirkland’s combination of drugs, dasatinib and quercetin, is known by the shorthand “D&Q” in the anti-aging community. After Kirkland showed that another drug, called fisetin, makes mice fed it live about 20% longer, self-experimenters didn’t delay in trying it.
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Just in case the longevity drugs don’t work, transhumanists like Clement have a backup plan. He wears a steel wristband directing anyone who finds his dead body to call the brain-freezing company Alcor, in Arizona, to preserve his brain for reanimation in the distant future.