Longevity escape velocity

Longevity escape velocity
August 16, 2019

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From The transhumanists who want to live forever on MIT Technology Review:

To Clement, though, my age was great news. “Yep, you are going to live forever,” he said. “I think anybody under 50 who does not have a genetic liability will make it to longevity escape velocity.”


With funds from wealthy elderly men he knows, he is independently exploring drugs known to extend the healthy life span of rodents. Using a calculator, he extrapolates what a suitable human dose might be, and then finds people who will take them.

If he thinks the results look safe and have a hint of promise, he will recommend the treatments to his parents, who are in their 90s, and to his financial supporters.


One potential aging treatment he is giving some 30 volunteers is a drug combination identified in 2015 at the Mayo Clinic by researcher James Kirkland as a way to selectively kill malfunctioning “senescent” cells in mice. Kirkland this year published his own pilot study exploring his treatment in 26 volunteers with pulmonary disease.
Kirkland’s combination of drugs, dasatinib and quercetin, is known by the shorthand “D&Q” in the anti-aging community. After Kirkland showed that another drug, called fisetin, makes mice fed it live about 20% longer, self-experimenters didn’t delay in trying it.


Just in case the longevity drugs don’t work, transhumanists like Clement have a backup plan. He wears a steel wristband directing anyone who finds his dead body to call the brain-freezing company Alcor, in Arizona, to preserve his brain for reanimation in the distant future.