Others who’d taken Basis before me had described effects including fingernail growth, hair growth, skin smoothness, crazy dreams, increased stamina, better sleep, and more energy. Once I began taking it, I did feel an almost jittery uptick in mojo for a few days, and I slept more soundly as well. Then those effects seemed to recede, and there were also mornings where I felt a little out of it. If these were placebo effects, they were weird ones, because they didn’t make me feel better, only different.
Because the two active compounds in Basis, pterostilbene and NR, are natural (occurring in blueberries and milk, respectively) and have long been available separately as supplements, Elysium has been able to skip the FDA gauntlet and sell its capsules immediately.
The agility that comes with bypassing federal regulation has an obvious cost: Guarente and his advisory board are the only scientific credibility Elysium can claim. The company stresses that it is using only compounds supported by hundreds of peer-reviewed papers, that it enforces high manufacturing standards, and that it is conducting a human trial (currently 120 people between the ages of 60 and 80 are participating).
but most importantly
A large number of men who have made fortunes in Silicon Valley believe so — or at least are trying to recast aging as merely another legacy system in need of recoding. Oracle co-founder Larry Ellison’s Ellison Medical Foundation has spent more than $400 million on aging research. In 2013, Alphabet’s Larry Page announced a moonshot life-extension project called Calico, and XPrize founder Peter Diamandis partnered with genome sequencer J. Craig Venter to found a competing company called Human Longevity Inc. Paul F. Glenn, an 85-year-old venture capitalist who watched his grandfather die of cancer, launched an aging-science foundation more than 50 years ago that has since funded a dozen aging-research centers around the country. Peter Thiel is 37 years Glenn’s junior but equally desperate to find a death cure: He has given at least $3 million to the Methuselah Foundation, the research vehicle for the extravagantly bearded, Barnumesque immortality promoter Aubrey de Grey. Thiel has also said he takes a daily dose of human growth hormone, and he was reported to have seriously explored the transfusion of blood from the young to the old.