CRISPR has revealed a clue in how human embryos begin to develop

From CRISPR breakthrough could drop miscarriage rates | TechCrunch

CRISPR Cas9 can modify or snip out genetic defects thought to contribute to miscarriage, but until now it wasn’t clear why some embryos continued to form into a fetus and others did not.

British scientists conducting the study found that a certain human genetic marker called OTC4 played an important role in the formation and development in the early stages of embryonic development. The scientists used CRISPR Cas9 to knock out this important gene in days-old human embryos and found that without it, these embryos ceased to attach or grow properly.

The findings could not only help us better understand why some women suffer more miscarriages than others, but it could also potentially greatly increase the rate of successful in vitro fertilization (IVF) procedures.